HNRPLL (HNRNPLL) (NM_138394) Human Recombinant Protein
Product Specifications
Background
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]) .[supplied by OMIM, Aug 2008]
Overview
Recombinant protein of human heterogeneous nuclear ribonucleoprotein L-like (HNRPLL), transcript variant 1
Synonyms
HNRPLL; SRRF
Gene ID
92906
UniProt
Q8WVV9, A0A0S2Z6K1
Accession Number mRNA
NM_138394
Chromosomal Location
2p22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
59.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HNRNPLL
Species
Human
Protein ID
NP_612403
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/92906
Uniprot URL
https://www.uniprot.org/uniprot/Q8WVV9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138394
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_612403
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