IFT43 (NM_052873) Human Recombinant Protein

Product Specifications

Background

This gene encodes a subunit of the intraflagellar transport complex A (IFT-A) . IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Overview

Recombinant protein of human chromosome 14 open reading frame 179 (C14orf179), transcript variant 1

Synonyms

C14orf179; CED3; RP81; SRTD18

Gene ID

112752

UniProt

Q96FT9, A0A024R6A9

Accession Number mRNA

NM_052873

Chromosomal Location

14q24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

23.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.