IFT43 (NM_052873) Human Recombinant Protein
Product Specifications
Background
This gene encodes a subunit of the intraflagellar transport complex A (IFT-A) . IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Synonyms
C14orf179; CED3; RP81; SRTD18
Gene ID
112752
UniProt
Q96FT9, A0A024R6A9
Accession Number mRNA
NM_052873
Chromosomal Location
14q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
23.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IFT43
Species
Human
Protein ID
NP_443105
Overview
Recombinant protein of human chromosome 14 open reading frame 179 (C14orf179), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/112752
Uniprot URL
https://www.uniprot.org/uniprot/Q96FT9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_052873
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_443105
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