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ARF6 (NM_001663) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human ADP-ribosylation factor 6 (ARF6)

Synonyms

DKFZp564M0264

Gene ID

382

UniProt

P62330

Accession Number mRNA

NM_001663

Chromosomal Location

14q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis, Fc gamma R-mediated phagocytosis

Field of Research

Endocytosis, Fc gamma R-mediated phagocytosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

19.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ARF6

Species

Human

Protein ID

NP_001654

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/382

Uniprot URL

https://www.uniprot.org/uniprot/P62330

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001663

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001654

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