BCKDH kinase (BCKDK) (NM_005881) Human Recombinant Protein
Product Specifications
Background
The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Synonyms
BCKDKD; BDK
Gene ID
10295
UniProt
O14874, A0A024QZA9
Accession Number mRNA
NM_005881
Chromosomal Location
16p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
46.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BCKDK
Species
Human
Protein ID
NP_005872
Overview
Recombinant protein of human branched chain ketoacid dehydrogenase kinase (BCKDK), nuclear gene encoding mitochondrial protein, transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10295
Uniprot URL
https://www.uniprot.org/uniprot/O14874
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005881
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005872
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