PANK3 (NM_024594) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human pantothenate kinase 3 (PANK3)

Synonyms

DKFZp686O22247; FLJ12899; MGC16863

Gene ID

79646

UniProt

Q9H999

Accession Number mRNA

NM_024594

Chromosomal Location

5q34

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Pantothenate and CoA biosynthesis

Field of Research

Metabolic pathways, Pantothenate and CoA biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

40.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.