PANK3 (NM_024594) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]
Synonyms
DKFZp686O22247; FLJ12899; MGC16863
Gene ID
79646
UniProt
Q9H999
Accession Number mRNA
NM_024594
Chromosomal Location
5q34
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Pantothenate and CoA biosynthesis
Field of Research
Metabolic pathways, Pantothenate and CoA biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
40.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PANK3
Species
Human
Protein ID
NP_078870
Overview
Recombinant protein of human pantothenate kinase 3 (PANK3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79646
Uniprot URL
https://www.uniprot.org/uniprot/Q9H999
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024594
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_078870
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