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EIF3D (NM_003753) Human Recombinant Protein

Product Specifications

Background

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human eukaryotic translation initiation factor 3, subunit D (EIF3D)

Synonyms

EIF3-p66; eIF3-zeta; EIF3S7

Gene ID

8664

UniProt

O15371

Accession Number mRNA

NM_003753

Chromosomal Location

22q12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

63.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EIF3D

Species

Human

Protein ID

NP_003744

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8664

Uniprot URL

https://www.uniprot.org/uniprot/O15371

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003753

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003744

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