EIF3D (NM_003753) Human Recombinant Protein
Product Specifications
Background
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human eukaryotic translation initiation factor 3, subunit D (EIF3D)
Synonyms
EIF3-p66; eIF3-zeta; EIF3S7
Gene ID
8664
UniProt
O15371
Accession Number mRNA
NM_003753
Chromosomal Location
22q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
63.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EIF3D
Species
Human
Protein ID
NP_003744
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8664
Uniprot URL
https://www.uniprot.org/uniprot/O15371
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003753
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003744
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