C1QC (NM_172369) Human Recombinant Protein

Product Specifications

Background

This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]

Overview

Recombinant protein of human complement component 1, q subcomponent, C chain (C1QC), transcript variant 2

Synonyms

C1Q-C; C1QG

Gene ID

714

UniProt

P02747, A0A024RAA7

Accession Number mRNA

NM_172369

Chromosomal Location

1p36.12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

Field of Research

Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

22.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.