C20orf72 (MGME1) (NM_052865) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Synonyms
BA504H3.4; C20orf72; DDK1; MTDPS11
Gene ID
92667
UniProt
Q9BQP7
Accession Number mRNA
NM_052865
Chromosomal Location
20p11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
39.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MGME1
Species
Human
Protein ID
NP_443097
Overview
Recombinant protein of human chromosome 20 open reading frame 72 (C20orf72)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/92667
Uniprot URL
https://www.uniprot.org/uniprot/Q9BQP7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_052865
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_443097
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