Adiponectin Receptor 1 (ADIPOR1) (NM_015999) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]

Overview

Recombinant protein of human adiponectin receptor 1 (ADIPOR1), transcript variant 1

Synonyms

ACDCR1; CGI-45; CGI45; PAQR1; TESBP1A

Gene ID

51094

UniProt

Q96A54

Accession Number mRNA

NM_015999

Chromosomal Location

1q32.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Adipocytokine signaling pathway

Field of Research

Adipocytokine signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

42.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.