COUP TF1 (NR2F1) (NM_005654) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS) . [provided by RefSeq, Apr 2014]
Overview
Recombinant protein of human nuclear receptor subfamily 2, group F, member 1 (NR2F1)
Synonyms
BBOAS; BBSOAS; COUP-TFI; EAR-3; EAR3; ERBAL3; NR2F2; SVP44; TCFCOUP1; TFCOUP1
Gene ID
7025
UniProt
P10589
Accession Number mRNA
NM_005654
Chromosomal Location
5q15
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Molecular Weight
46 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NR2F1
Species
Human
Protein ID
NP_005645
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7025
Uniprot URL
https://www.uniprot.org/uniprot/P10589
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005654
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005645
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