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COUP TF1 (NR2F1) (NM_005654) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS) . [provided by RefSeq, Apr 2014]

Overview

Recombinant protein of human nuclear receptor subfamily 2, group F, member 1 (NR2F1)

Synonyms

BBOAS; BBSOAS; COUP-TFI; EAR-3; EAR3; ERBAL3; NR2F2; SVP44; TCFCOUP1; TFCOUP1

Gene ID

7025

UniProt

P10589

Accession Number mRNA

NM_005654

Chromosomal Location

5q15

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Molecular Weight

46 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NR2F1

Species

Human

Protein ID

NP_005645

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7025

Uniprot URL

https://www.uniprot.org/uniprot/P10589

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005654

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005645

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