Gamma Adaptin (AP1G1) (NM_001030007) Human Recombinant Protein
Product Specifications
Background
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
ADTG; CLAPG1
Gene ID
164
UniProt
O43747, A0A140VJE7, Q8IY97
Accession Number mRNA
NM_001030007
Chromosomal Location
16q22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Lysosome
Field of Research
Lysosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
91.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AP1G1
Species
Human
Protein ID
NP_001025178
Overview
Recombinant protein of human adaptor-related protein complex 1, gamma 1 subunit (AP1G1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/164
Uniprot URL
https://www.uniprot.org/uniprot/O43747
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001030007
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001025178
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