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Gamma Adaptin (AP1G1) (NM_001030007) Human Recombinant Protein

Product Specifications

Background

Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

ADTG; CLAPG1

Gene ID

164

UniProt

O43747, A0A140VJE7, Q8IY97

Accession Number mRNA

NM_001030007

Chromosomal Location

16q22.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Lysosome

Field of Research

Lysosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

91.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AP1G1

Species

Human

Protein ID

NP_001025178

Overview

Recombinant protein of human adaptor-related protein complex 1, gamma 1 subunit (AP1G1), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/164

Uniprot URL

https://www.uniprot.org/uniprot/O43747

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001030007

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001025178

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