DP1 (TFDP1) (NM_007111) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]
Overview
Recombinant protein of human transcription factor Dp-1 (TFDP1), transcript variant 1
Synonyms
DILC; Dp-1; DP1; DRTF1
Gene ID
7027
UniProt
Q14186, A0A024RDY4
Accession Number mRNA
NM_007111
Chromosomal Location
13q34
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell cycle, TGF-beta signaling pathway
Field of Research
Cell cycle, TGF-beta signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
44.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TFDP1
Species
Human
Protein ID
NP_009042
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7027
Uniprot URL
https://www.uniprot.org/uniprot/Q14186
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007111
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009042
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