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CORO2A (NM_052820) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human coronin, actin binding protein, 2A (CORO2A), transcript variant 2

Synonyms

CLIPINB; IR10; WDR2

Gene ID

7464

UniProt

Q92828, A0A024R150, A8K9S3

Accession Number mRNA

NM_052820

Chromosomal Location

9q22.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

59.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CORO2A

Species

Human

Protein ID

NP_438171

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7464

Uniprot URL

https://www.uniprot.org/uniprot/Q92828

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_052820

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_438171

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