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Tropomyosin 2 (TPM2) (NM_213674) Human Recombinant Protein

Product Specifications

Background

This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

Synonyms

AMCD1; DA1; DA2B; DA2B4; HEL-S-273; NEM4; TMSB

Gene ID

7169

UniProt

P07951, V9HW25

Accession Number mRNA

NM_213674

Chromosomal Location

9p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Field of Research

Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

32.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TPM2

Species

Human

Protein ID

NP_998839

Overview

Recombinant protein of human tropomyosin 2 (beta) (TPM2), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7169

Uniprot URL

https://www.uniprot.org/uniprot/P07951

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_213674

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_998839

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