Tropomyosin 2 (TPM2) (NM_213674) Human Recombinant Protein
Product Specifications
Background
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Overview
Recombinant protein of human tropomyosin 2 (beta) (TPM2), transcript variant 2
Synonyms
AMCD1; DA1; DA2B; DA2B4; HEL-S-273; NEM4; TMSB
Gene ID
7169
UniProt
P07951, V9HW25
Accession Number mRNA
NM_213674
Chromosomal Location
9p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Field of Research
Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
32.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TPM2
Species
Human
Protein ID
NP_998839
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7169
Uniprot URL
https://www.uniprot.org/uniprot/P07951
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_213674
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_998839
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