COTL1 (NM_021149) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]
Synonyms
CLP
Gene ID
23406
UniProt
Q14019, A0A384MTY2
Accession Number mRNA
NM_021149
Chromosomal Location
16q24.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
15.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
COTL1
Species
Human
Protein ID
NP_066972
Overview
Recombinant protein of human coactosin-like 1 (Dictyostelium) (COTL1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23406
Uniprot URL
https://www.uniprot.org/uniprot/Q14019
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021149
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_066972
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