PPCDC (NM_021823) Human Recombinant Protein
Product Specifications
Background
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]) .[supplied by OMIM, Mar 2008]
Synonyms
CoaC; MDS018; PPC-DC
Gene ID
60490
UniProt
Q96CD2
Accession Number mRNA
NM_021823
Chromosomal Location
15q24.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Pantothenate and CoA biosynthesis
Field of Research
Metabolic pathways, Pantothenate and CoA biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
22.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPCDC
Species
Human
Protein ID
NP_068595
Overview
Recombinant protein of human phosphopantothenoylcysteine decarboxylase (PPCDC)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/60490
Uniprot URL
https://www.uniprot.org/uniprot/Q96CD2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021823
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_068595
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