PPCDC (NM_021823) Human Recombinant Protein

Product Specifications

Background

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]) .[supplied by OMIM, Mar 2008]

Overview

Recombinant protein of human phosphopantothenoylcysteine decarboxylase (PPCDC)

Synonyms

CoaC; MDS018; PPC-DC

Gene ID

60490

UniProt

Q96CD2

Accession Number mRNA

NM_021823

Chromosomal Location

15q24.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Pantothenate and CoA biosynthesis

Field of Research

Metabolic pathways, Pantothenate and CoA biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

22.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.