RNMTL1 (MRM3) (NM_018146) Human Recombinant Protein
Product Specifications
Background
Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G (1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Synonyms
RMTL1; RNMTL1
Gene ID
55178
UniProt
Q9HC36
Accession Number mRNA
NM_018146
Chromosomal Location
17p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Stem cell - Pluripotency
Molecular Weight
46.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MRM3
Species
Human
Protein ID
NP_060616
Overview
Recombinant protein of human RNA methyltransferase like 1 (RNMTL1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55178
Uniprot URL
https://www.uniprot.org/uniprot/Q9HC36
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018146
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060616
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