Bone marrow stromal cell antigen 1 (BST1) (NM_004334) Human Recombinant Protein
Product Specifications
Background
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human bone marrow stromal cell antigen 1 (BST1)
Synonyms
CD157
Gene ID
683
UniProt
Q10588
Accession Number mRNA
NM_004334
Chromosomal Location
4p15.32
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Calcium signaling pathway, Metabolic pathways, Nicotinate and nicotinamide metabolism
Field of Research
Calcium signaling pathway, Metabolic pathways, Nicotinate and nicotinamide metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
35.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BST1
Species
Human
Protein ID
NP_004325
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/683
Uniprot URL
https://www.uniprot.org/uniprot/Q10588
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004334
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004325
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