PP1C gamma (PPP1CC) (NM_002710) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms
PP-1G; PP1C; PPP1G
Gene ID
5501
UniProt
P36873, A0A024RBP2
Accession Number mRNA
NM_002710
Chromosomal Location
12q24.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Focal adhesion, Insulin signaling pathway, Long-term potentiation, Oocyte meiosis, Regulation of actin cytoskeleton, Vascular smooth muscle contraction
Field of Research
Focal adhesion, Insulin signaling pathway, Long-term potentiation, Oocyte meiosis, Regulation of actin cytoskeleton, Vascular smooth muscle contraction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase
Molecular Weight
36.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPP1CC
Species
Human
Protein ID
NP_002701
Overview
Recombinant protein of human protein phosphatase 1, catalytic subunit, gamma isoform (PPP1CC)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5501
Uniprot URL
https://www.uniprot.org/uniprot/P36873
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002710
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002701
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