Prostaglandin dehydrogenase 1 (HPGD) (NM_000860) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Overview
Recombinant protein of human hydroxyprostaglandin dehydrogenase 15- (NAD) (HPGD), transcript variant 1
Synonyms
15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1
Gene ID
3248
UniProt
P15428
Accession Number mRNA
NM_000860
Chromosomal Location
4q34.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
28.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HPGD
Species
Human
Protein ID
NP_000851
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3248
Uniprot URL
https://www.uniprot.org/uniprot/P15428
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000860
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000851
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog