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Prostaglandin dehydrogenase 1 (HPGD) (NM_000860) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Overview

Recombinant protein of human hydroxyprostaglandin dehydrogenase 15- (NAD) (HPGD), transcript variant 1

Synonyms

15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1

Gene ID

3248

UniProt

P15428

Accession Number mRNA

NM_000860

Chromosomal Location

4q34.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

28.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HPGD

Species

Human

Protein ID

NP_000851

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3248

Uniprot URL

https://www.uniprot.org/uniprot/P15428

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000860

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000851

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