PEDF (SERPINF1) (NM_002615) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]
Synonyms
EPC-1; OI6; OI12; PEDF; PIG35
Gene ID
5176
UniProt
P36955, A0A140VKF3
Accession Number mRNA
NM_002615
Chromosomal Location
17p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
46.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SERPINF1
Species
Human
Protein ID
NP_002606
Overview
Recombinant protein of human serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (SERPINF1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5176
Uniprot URL
https://www.uniprot.org/uniprot/P36955
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002615
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002606
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items