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IGFBP4 (NM_001552) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human insulin-like growth factor binding protein 4 (IGFBP4)

Synonyms

BP-4; HT29-IGFBP; IBP4; IGFBP-4

Gene ID

3487

UniProt

P22692, A0A024R1U8

Accession Number mRNA

NM_001552

Chromosomal Location

17q21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

25.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

IGFBP4

Species

Human

Protein ID

NP_001543

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3487

Uniprot URL

https://www.uniprot.org/uniprot/P22692

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001552

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001543

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