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HOXB6 (NM_018952) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human homeobox B6 (HOXB6)

Synonyms

Hox-2.2; HOX2; HOX2B; HU-2

Gene ID

3216

UniProt

P17509

Accession Number mRNA

NM_018952

Chromosomal Location

17q21.32

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

25.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HOXB6

Species

Human

Protein ID

NP_061825

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3216

Uniprot URL

https://www.uniprot.org/uniprot/P17509

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018952

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_061825

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