Claudin 2 (CLDN2) (NM_020384) Human Recombinant Protein
Product Specifications
Background
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
Synonyms
SP82
Gene ID
9075
UniProt
P57739
Accession Number mRNA
NM_020384
Chromosomal Location
Xq22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Field of Research
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
24.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CLDN2
Species
Human
Protein ID
NP_065117
Overview
Recombinant protein of human claudin 2 (CLDN2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9075
Uniprot URL
https://www.uniprot.org/uniprot/P57739
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020384
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065117
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