DPH3 (NM_206831) Human Recombinant Protein
Product Specifications
Background
This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]
Synonyms
DELGIP; DELGIP1; DESR1; DPH3A; KTI11; ZCSL2
Gene ID
285381
UniProt
Q96FX2
Accession Number mRNA
NM_206831
Chromosomal Location
3p25.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
9.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DPH3
Species
Human
Protein ID
NP_996662
Overview
Recombinant protein of human DPH3, KTI11 homolog (S. cerevisiae) (DPH3), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/285381
Uniprot URL
https://www.uniprot.org/uniprot/Q96FX2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_206831
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_996662
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