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G protein alpha Inhibitor 2 (GNAI2) (NM_002070) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins) . The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Synonyms

GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1

Gene ID

2771

UniProt

P04899, B3KP24

Accession Number mRNA

NM_002070

Chromosomal Location

3p21.31

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction

Field of Research

Axon guidance, Chemokine signaling pathway, Gap junction, Leukocyte transendothelial migration, Long-term depression, Melanogenesis, Progesterone-mediated oocyte maturation, Tight junction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

40.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GNAI2

Species

Human

Protein ID

NP_002061

Overview

Recombinant protein of human guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2771

Uniprot URL

https://www.uniprot.org/uniprot/P04899

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002070

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002061

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