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MTRF1L (NM_019041) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Overview

Recombinant protein of human mitochondrial translational release factor 1-like (MTRF1L), nuclear gene encoding mitochondrial protein, transcript variant 1

Synonyms

HMRF1L; MRF1L; mtRF1a

Gene ID

54516

UniProt

Q9UGC7

Accession Number mRNA

NM_019041

Chromosomal Location

6q25.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

43.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MTRF1L

Species

Human

Protein ID

NP_061914

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/54516

Uniprot URL

https://www.uniprot.org/uniprot/Q9UGC7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_019041

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_061914

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