TID1 (DNAJA3) (NM_005147) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Overview
Purified recombinant protein of Homo sapiens DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 1
Synonyms
HCA57; hTID-1; TID1
Gene ID
9093
UniProt
Q96EY1, Q53G26, Q59E88
Accession Number mRNA
NM_005147
Chromosomal Location
16p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
52.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DNAJA3
Species
Human
Protein ID
NP_005138
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9093
Uniprot URL
https://www.uniprot.org/uniprot/Q96EY1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005147
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005138
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