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C7orf30 (MALSU1) (NM_138446) Human Recombinant Protein

Product Specifications

Background

Required for normal mitochondrial ribosome function and mitochondrial translation (PubMed:22238375, PubMed:23171548) . May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable) . Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable) . Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable) . May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (PubMed:22238376, PubMed:23171548) . May function as a ribosomal silencing factor (Probable) .[UniProtKB/Swiss-Prot Function]

Synonyms

C7orf30; mtRsfA

Gene ID

115416

UniProt

Q96EH3

Accession Number mRNA

NM_138446

Chromosomal Location

7p15.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

26 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MALSU1

Species

Human

Protein ID

NP_612455

Overview

Recombinant protein of human chromosome 7 open reading frame 30 (C7orf30)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/115416

Uniprot URL

https://www.uniprot.org/uniprot/Q96EH3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_138446

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_612455

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