GMP Synthase (GMPS) (NM_003875) Human Recombinant Protein
Product Specifications
Background
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human guanine monphosphate synthetase (GMPS)
Synonyms
GATD7
Gene ID
8833
UniProt
P49915, A0A140VJK6
Accession Number mRNA
NM_003875
Chromosomal Location
3q25.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
Field of Research
Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Stem cell - Pluripotency
Molecular Weight
76.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GMPS
Species
Human
Protein ID
NP_003866
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8833
Uniprot URL
https://www.uniprot.org/uniprot/P49915
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003875
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003866
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