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PARP3 (NM_005485) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly (ADP-ribosyl) transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2

Synonyms

ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3

Gene ID

10039

UniProt

Q9Y6F1, A0A024R318

Accession Number mRNA

NM_005485

Chromosomal Location

3p21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Base excision repair

Field of Research

Base excision repair

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

59.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PARP3

Species

Human

Protein ID

NP_005476

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10039

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y6F1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005485

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005476

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