PARP3 (NM_005485) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly (ADP-ribosyl) transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2
Synonyms
ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3
Gene ID
10039
UniProt
Q9Y6F1, A0A024R318
Accession Number mRNA
NM_005485
Chromosomal Location
3p21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Base excision repair
Field of Research
Base excision repair
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
59.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PARP3
Species
Human
Protein ID
NP_005476
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10039
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y6F1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005485
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005476
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