GNLY (NM_006433) Human Recombinant Protein
Product Specifications
Background
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human granulysin (GNLY), transcript variant NKG5
Synonyms
D2S69E; LAG-2; LAG2; NKG5; TLA519
Gene ID
10578
UniProt
P22749
Accession Number mRNA
NM_006433
Chromosomal Location
2p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
16.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GNLY
Species
Human
Protein ID
NP_006424
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10578
Uniprot URL
https://www.uniprot.org/uniprot/P22749
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006433
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006424
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