HNRPAB (HNRNPAB) (NM_031266) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
ABBP1; HNRPAB
Gene ID
3182
UniProt
Q99729
Accession Number mRNA
NM_031266
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
35.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HNRNPAB
Species
Human
Protein ID
NP_112556
Overview
Recombinant protein of human heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3182
Uniprot URL
https://www.uniprot.org/uniprot/Q99729
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031266
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112556
Curated Selection
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