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NUP93 (NM_014669) Human Recombinant Protein

Product Specifications

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

Overview

Recombinant protein of human nucleoporin 93kDa (NUP93)

Synonyms

NIC96

Gene ID

9688

UniProt

Q8N1F7

Accession Number mRNA

NM_014669

Chromosomal Location

16q13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

93.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NUP93

Species

Human

Protein ID

NP_055484

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9688

Uniprot URL

https://www.uniprot.org/uniprot/Q8N1F7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014669

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055484

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