Rabex5 (RABGEF1) (NM_014504) Human Recombinant Protein
Product Specifications
Background
RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]) .[supplied by OMIM, Mar 2010]
Synonyms
Rabex-5; RABEX5; RAP1
Gene ID
27342
UniProt
Q9UJ41, A0A024RDL6, A0A0A0MSJ3
Accession Number mRNA
NM_014504
Chromosomal Location
7q11.21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
56.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RABGEF1
Species
Human
Protein ID
NP_055319
Overview
Recombinant protein of human RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27342
Uniprot URL
https://www.uniprot.org/uniprot/Q9UJ41
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014504
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055319
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