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Rabex5 (RABGEF1) (NM_014504) Human Recombinant Protein

Product Specifications

Background

RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]) .[supplied by OMIM, Mar 2010]

Overview

Recombinant protein of human RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1)

Synonyms

Rabex-5; RABEX5; RAP1

Gene ID

27342

UniProt

Q9UJ41, A0A024RDL6, A0A0A0MSJ3

Accession Number mRNA

NM_014504

Chromosomal Location

7q11.21

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

56.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RABGEF1

Species

Human

Protein ID

NP_055319

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/27342

Uniprot URL

https://www.uniprot.org/uniprot/Q9UJ41

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014504

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055319

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