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ICT1 (MRPL58) (NM_001545) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Overview

Recombinant protein of human immature colon carcinoma transcript 1 (ICT1)

Synonyms

DS-1; DS1; ICT1; MRP-L58

Gene ID

3396

UniProt

Q14197

Accession Number mRNA

NM_001545

Chromosomal Location

17q25.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

23.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MRPL58

Species

Human

Protein ID

NP_001536

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3396

Uniprot URL

https://www.uniprot.org/uniprot/Q14197

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001545

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001536

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