ICT1 (MRPL58) (NM_001545) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
Synonyms
DS-1; DS1; ICT1; MRP-L58
Gene ID
3396
UniProt
Q14197
Accession Number mRNA
NM_001545
Chromosomal Location
17q25.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
23.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MRPL58
Species
Human
Protein ID
NP_001536
Overview
Recombinant protein of human immature colon carcinoma transcript 1 (ICT1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3396
Uniprot URL
https://www.uniprot.org/uniprot/Q14197
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001545
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001536
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