TRP2 (DCT) (NM_001922) Human Recombinant Protein
Product Specifications
Background
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:8306979) . Involved in regulating eumelanin and phaeomelanin levels.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) (DCT), transcript variant 1
Synonyms
TRP-2; TYRP2
Gene ID
1638
UniProt
P40126
Accession Number mRNA
NM_001922
Chromosomal Location
13q32.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Melanogenesis, Metabolic pathways, Tyrosine metabolism
Field of Research
Melanogenesis, Metabolic pathways, Tyrosine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
59 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DCT
Species
Human
Protein ID
NP_001913
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1638
Uniprot URL
https://www.uniprot.org/uniprot/P40126
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001922
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001913
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