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Psoriasin (S100A7) (NM_002963) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]

Overview

Recombinant protein of human S100 calcium binding protein A7 (S100A7)

Synonyms

PSOR1; S100A7c

Gene ID

6278

UniProt

P31151

Accession Number mRNA

NM_002963

Chromosomal Location

1q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

11.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

S100A7

Species

Human

Protein ID

NP_002954

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6278

Uniprot URL

https://www.uniprot.org/uniprot/P31151

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002963

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002954

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