MITD1 (NM_138798) Human Recombinant Protein
Product Specifications
Background
Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III) . The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Synonyms
Domain containing 1; microtubule interacting and transport; MIT
Gene ID
129531
UniProt
Q8WV92
Accession Number mRNA
NM_138798
Chromosomal Location
2q11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
29.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MITD1
Species
Human
Protein ID
NP_620153
Overview
Recombinant protein of human MIT, microtubule interacting and transport, domain containing 1 (MITD1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/129531
Uniprot URL
https://www.uniprot.org/uniprot/Q8WV92
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138798
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_620153
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