GEF H1 (ARHGEF2) (NM_004723) Human Recombinant Protein
Product Specifications
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]
Synonyms
GEF; GEF-H1; GEFH1; Lfc; LFP40; NEDMHM; P40
Gene ID
9181
UniProt
Q92974
Accession Number mRNA
NM_004723
Chromosomal Location
1q22
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Pathogenic Escherichia coli infection
Field of Research
Pathogenic Escherichia coli infection
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
108.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARHGEF2
Species
Human
Protein ID
NP_004714
Overview
Recombinant protein of human rho/rac guanine nucleotide exchange factor (GEF) 2 (ARHGEF2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9181
Uniprot URL
https://www.uniprot.org/uniprot/Q92974
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004723
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004714
Curated Selection
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