GEF H1 (ARHGEF2) (NM_004723) Human Recombinant Protein

Product Specifications

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]

Overview

Recombinant protein of human rho/rac guanine nucleotide exchange factor (GEF) 2 (ARHGEF2)

Synonyms

GEF; GEF-H1; GEFH1; Lfc; LFP40; NEDMHM; P40

Gene ID

9181

UniProt

Q92974

Accession Number mRNA

NM_004723

Chromosomal Location

1q22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Pathogenic Escherichia coli infection

Field of Research

Pathogenic Escherichia coli infection

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

108.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.