GFAP (NM_002055) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Overview
Recombinant protein of human glial fibrillary acidic protein (GFAP), transcript variant 1
Synonyms
ALXDRD
Gene ID
2670
UniProt
P14136, A7REI1
Accession Number mRNA
NM_002055
Chromosomal Location
17q21.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
29774780
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
ES Cell Differentiation/IPS
Molecular Weight
49.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GFAP
Species
Human
Protein ID
NP_002046
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2670
Uniprot URL
https://www.uniprot.org/uniprot/P14136
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002055
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002046
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