RRAS2 (NM_012250) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Overview

Recombinant protein of human related RAS viral (r-ras) oncogene homolog 2 (RRAS2), transcript variant 1

Synonyms

NS12; TC21

Gene ID

22800

UniProt

P62070

Accession Number mRNA

NM_012250

Chromosomal Location

11p15.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction

Field of Research

MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

23.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.