TFIIB (GTF2B) (NM_001514) Human Recombinant Protein
Product Specifications
Background
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human general transcription factor IIB (GTF2B)
Synonyms
TF2B; TFIIB
Gene ID
2959
UniProt
Q00403
Accession Number mRNA
NM_001514
Chromosomal Location
1p22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Basal transcription factors
Field of Research
Basal transcription factors
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
34.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GTF2B
Species
Human
Protein ID
NP_001505
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2959
Uniprot URL
https://www.uniprot.org/uniprot/Q00403
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001514
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001505
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