ACN9 (SDHAF3) (NM_020186) Human Recombinant Protein
Product Specifications
Background
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.[UniProtKB/Swiss-Prot Function]
Synonyms
ACN9; DC11; LYRM10; Sdh7
Gene ID
57001
UniProt
Q9NRP4
Accession Number mRNA
NM_020186
Chromosomal Location
7q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
14.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SDHAF3
Species
Human
Protein ID
NP_064571
Overview
Recombinant protein of human ACN9 homolog (S. cerevisiae) (ACN9)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57001
Uniprot URL
https://www.uniprot.org/uniprot/Q9NRP4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020186
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_064571
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