RBP4 (NM_006744) Human Recombinant Protein
Product Specifications
Background
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human retinol binding protein 4, plasma (RBP4)
Synonyms
MCOPCB10; RDCCAS
Gene ID
5950
UniProt
P02753
Accession Number mRNA
NM_006744
Chromosomal Location
10q23.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
21 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RBP4
Species
Human
Protein ID
NP_006735
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5950
Uniprot URL
https://www.uniprot.org/uniprot/P02753
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006744
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006735
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