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FCN1 (NM_002003) Human Recombinant Protein

Product Specifications

Background

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human ficolin (collagen/fibrinogen domain containing) 1 (FCN1)

Synonyms

FCNM

Gene ID

2219

UniProt

O00602

Accession Number mRNA

NM_002003

Chromosomal Location

9q34.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

32.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FCN1

Species

Human

Protein ID

NP_001994

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2219

Uniprot URL

https://www.uniprot.org/uniprot/O00602

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002003

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001994

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