FCN1 (NM_002003) Human Recombinant Protein
Product Specifications
Background
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human ficolin (collagen/fibrinogen domain containing) 1 (FCN1)
Synonyms
FCNM
Gene ID
2219
UniProt
O00602
Accession Number mRNA
NM_002003
Chromosomal Location
9q34.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
32.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FCN1
Species
Human
Protein ID
NP_001994
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2219
Uniprot URL
https://www.uniprot.org/uniprot/O00602
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002003
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001994
Frequently Asked Questions
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